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Publication  ·  2022

Why hair loss matters before laser resurfacing

Extensive facial scarring after ablative laser resurfacing in a patient with frontal fibrosing alopecia

A woman had a routine ablative laser resurfacing, healed normally, and then scarred extensively across her whole face. The reason was a hair-loss condition nobody had diagnosed — because skin heals from stem cells that live in hair follicles, and hers were gone.

Peer reviewed

Cong Sun, Davin Lim, Philip Bekhor

JAAD Case Reports, 2022  ·  Case report

DOI 10.1016/j.jdcr.2022.03.024

What the study found

Four numbers worth knowing

12 daysto complete healing — which looked entirely normal at the time
7 weeksbefore extensive scarring appeared across the treated areas
95%of people with this condition lose their eyebrows — the visible clue
16 weeksto full resolution once the right revision treatment started
The findings

What we found

  1. The procedure and the early healing were unremarkable.

    A 63-year-old woman had fully ablative erbium laser resurfacing for pigmentation and lines, at conservative settings. Erosions appeared on day six and were swabbed — all negative for bacteria and viruses. Healing completed by day twelve, with the residual redness settling over the following five weeks. Nothing about it looked like trouble.

  2. Then extensive scarring appeared over the whole treatment field.

    At seven weeks, hypertrophic scarring had developed across the treated areas, worst on the forehead and around the mouth.

  3. The diagnosis was visible on her face, and had never been made.

    At that same appointment the features of frontal fibrosing alopecia were recognised: loss of both eyebrows, band-like recession of the frontal hairline, and complete loss of facial vellus hair. Biopsies in front of the ear showed complete absence of hair follicles and glands — end-stage scarring alopecia.

  4. Skin heals from stem cells that live in hair follicles.

    Re-epithelialisation after full-thickness wounding depends on stem cells in the bulge region of the hair follicle. Frontal fibrosing alopecia destroys those follicles through progressive immune attack and fibrosis. Without enough of them, ablating the full thickness of the skin removes the very thing the skin needs to rebuild itself.

  5. The revision worked because it did not wound.

    Three weekly sessions of low-density non-ablative CO₂ laser, with topical triamcinolone under three-hour occlusion, a pulsed topical steroid regimen and silicone gel. Non-ablative treatment creates zones of thermal injury without destroying epidermal and dermal structures, which triggers remodelling through collagen and matrix metalloproteinase pathways — a process that does not need follicular stem cells.

  6. Complete resolution, and it held.

    Sixteen weeks after the original resurfacing the scarring had fully resolved, with no recurrence at twelve months.

  7. This was the first reported case of its kind.

    To the authors' knowledge, the first published case of extensive facial scarring after ablative resurfacing in a patient with undiagnosed frontal fibrosing alopecia.

In practice

What this means for you

Mention your eyebrows

Eyebrow loss occurs in up to 95% of frontal fibrosing alopecia cases and is often the first sign. If your eyebrows have thinned and you have put it down to age or over-plucking, say so before any resurfacing.

A receding frontal hairline is not only a male thing

Band-like recession of the hairline, particularly in postmenopausal women, is the other classic feature. It is frequently mistaken for ordinary thinning.

Loss of the fine facial hair is a clue too

Complete loss of the soft vellus hair on the face was present in this patient. It is subtle, and it is worth a direct look before ablative treatment.

Fully ablative is not the only option

Non-ablative treatment worked here precisely because it does not depend on follicular stem cells for healing. Where scarring alopecia is suspected, that distinction matters more than the brand of device.

Normal early healing does not clear you

This patient healed completely by day twelve. The scarring appeared at seven weeks. An uneventful first fortnight is not the same as an uneventful outcome.

Background

Why this matters

Frontal fibrosing alopecia is a scarring hair loss condition, a subvariant of lichen planopilaris, and its incidence has risen markedly in recent years. It is often symptomless, which is why it goes undiagnosed — and postmenopausal women make up the majority of those affected.

Ablative laser resurfacing works by removing the full thickness of the epidermis and letting it regenerate. That regeneration is driven by stem cells in the hair follicles. In a condition that destroys hair follicles, the arithmetic is obvious in hindsight and easy to miss in advance.

The message the authors wanted to send

Recognise scarring alopecia — or the possibility of it — in any patient presenting for laser therapy, and avoid ablative procedures where it is present. The complication is serious, and it is avoidable by looking at the eyebrows and the hairline before the laser is switched on.

Method

Who was studied

A single case report: a 63-year-old woman treated with fully ablative erbium 2940 nm laser for pigmentation and lines, with photographic and histological documentation through to twelve-month follow-up.

Patient
63-year-old woman
Laser
Erbium 2940 nm, fully ablative
Scarring noted
7 weeks
Resolved
16 weeks
Follow-up
12 months
Honesty

What this study cannot tell you

Every study has a boundary, and it is fairer to state it than to leave you to guess.

  • A single case. It establishes that this can happen, not how often it does.
  • The alopecia was diagnosed after the complication, so nothing here shows that screening would reliably have prevented it — only that the features were present and visible.
  • The revision protocol combined non-ablative laser, topical steroid under occlusion and silicone gel simultaneously, so the contribution of each cannot be separated.
  • The mechanism proposed — loss of follicular stem cells impairing re-epithelialisation — is well supported biologically but was not directly demonstrated in this patient.
  • Follow-up was twelve months. Longer-term stability is not reported.
Common questions

Questions people actually ask

Can laser resurfacing cause scarring?

Hypertrophic scarring is a recognised but rare complication of ablative laser resurfacing. The common effects are redness and swelling, which settle.

What this case shows is that an underlying scarring hair loss condition can turn a low-risk procedure into a high-risk one, because the skin's capacity to rebuild itself depends on hair follicles that the condition has destroyed.

What is frontal fibrosing alopecia?

A scarring form of hair loss, most common in postmenopausal women, in which the hairline recedes in a band-like pattern and the hair follicles are permanently destroyed by an immune-mediated inflammatory process.

Eyebrow loss occurs in up to 95% of cases and is often the earliest sign. It is frequently symptomless, which is why it goes undiagnosed.

Should I have laser if I have thinning eyebrows or a receding hairline?

It is a conversation to have before booking, not a reason to rule treatment out. The concern is specifically with fully ablative resurfacing, which removes the full thickness of the epidermis and relies on hair follicles to rebuild it.

In this case, non-ablative laser was used for the scar revision and worked well, because it stimulates remodelling without requiring those follicular stem cells.

Was the scarring permanent?

No. It resolved completely sixteen weeks after the original procedure, with a combination of low-density non-ablative CO₂ laser, topical steroid under occlusion and silicone gel, and there was no recurrence at twelve months.

Reference

Cite this paper

Sun C, Lim D, Bekhor P. Extensive facial scarring after ablative laser resurfacing in a patient with frontal fibrosing alopecia. JAAD Case Reports. 2022. doi:10.1016/j.jdcr.2022.03.024

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Published 2022  ·  Summary written and reviewed by Dr Davin Lim, FACD  ·  General information, not personal medical advice.

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